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Chemical Name:Tamoxifen citrate
SynonymsNOLVADEX;TMX;tamoxifene;SoltaMox;Nolvadex(Tamoxifen);(Z)-[2-[4-(1,2-diphenylbut-1-enyl)phenoxy]ethyl]dimethylammonium dihydrogen 2-hydroxypropane-1,2,3-tricarboxylate;TMX1;TXNDC;Adopan;kessar
CBNumber:CB7853805
Molecular Formula:C32H37NO8
Molecular Weight:563.64
Melting point 140-144 °C
storage temp. 2-8°C
solubility methanol: soluble50mg/mL, clear, colorless
form Powder
color White to off-white
Water Solubility slightly soluble
Sensitive Light Sensitive & Hygroscopic
Uses
Tamoxifen citrate is commonly used in the treatment of women with metastatic carcinoma of the breast to prevent recurrence after surgery or radiation treatment, and as prophylaxis for patients at very high risk to develop breast cancer.
Uses
anti-estrogen, protein kinase C inhibitor, beneficial cardiovascular effects, bone cancer treatment, induces DNA adduct formation
Uses
Tamoxifen Citrate is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4.