Basic information Chlorhexidine digluconate CAS no. 18472-51-0:

 

Product Name	Chlorhexidine digluconate
Synonyms	alpha.-Cymen-5-ol;1,1'-hexamethylenebis(5-(p-chlorophenyl)-biguaniddigluconate;1,6-bis(5-(p-chlorophenyl)biguandino)hexanedigluconate;3-Methyl-4-(1-methylethyl)phenol;abacil;arlacideg;bacticlens;caswellno.481g
CAS	18472-51-0
MF	C34H54Cl2N10O14
MW	897.76
EINECS	242-354-0
Product Categories	API;Broad-spectrum antimicrobial, bactericidal effect;Disinfectant

 

Chemical Properties Chlorhexidine digluconate CAS no. 18472-51-0:

 

 

color	Colorless
form	Liquid
density	1.06 g/mL at 25 °C(lit.)
Fp	Light Sensitive
storage temp.	2-8°C
Sensitive	water: soluble50% (w/v)
EPA Substance Registry System	D-Gluconic acid, compd. with N,N''-bis(4-chlorophenyl)- 3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide (2:1)(18472-51-0)
Merck	14,2091

 

Spec. Chlorhexidine digluconate CAS no. 18472-51-0:

 

Test	Specification	Result
Identification
A: IR Spectrum	To match with reference standard	complies
B: By TLC	To match with reference standard	complies
C: Chlorhexidine Mp	Chlorhexidine Mp 132°C~136°C	complies
D: Bromine R test	Positive reaction	Positive reaction
Tests
relative density	Betweeen 1.06 to 1.07	1.061
pH (5%)	Between 5.5 to 7.0	6.08
Chloroaniline	Maximum 0.25%	complies
Related substances (Examine by HPLC)	Not more thaan 3.0%	2.20%
Assay	Chlorhenxidine gluconate solution contain not less 190g/l and notmore than 210g/l of 1,1-(hexane- diyl)bis[5-(4-chlorphenyl)biguanide]du-D-gluconate	199g/l

 

Chlorhexidine digluconate is Colourless or pale - yellowish liquid, miscible ,transparent liquid, odorless, miscible with water, sparingly soluble in alcohol and acetone.

 

 Chlorhexidine Gluconate is a powerful anti-microbial agent. It is notable for its effectiveness for killing a wide range of bacteria, including both gram-positive and gram-negative bacteria (the two largest classes of bacteria). It is also an effective anti-fungal and anti-spore agent. Chlorhexidine digluconate is commonly used as an active ingredient in germicidal mouthwash, pet shampoo, surgical lubricants and wipes, and hand soap.

 

 Chlorhexidine Gluconate is a powerful anti-microbial agent. It is notable for its effectiveness for killing a wide range of bacteria, including both gram-positive and gram-negative bacteria (the two largest classes of bacteria). It is also an effective anti-fungal and anti-spore agent. Chlorhexidine digluconate is commonly used as an active ingredient in germicidal mouthwash, pet shampoo, surgical lubricants and wipes, and hand soap.

 

Chlorhexidine Gluconate, has a strong broad-spectrum antibacterial and bactericidal effect, and is effective against both Gram-positive and Gram-negative bacteria. Disinfect the hands and skin, and rinse the wound.

 

• In cosmetics and personal care products, Chlorhexidine and its salts (Chlorohexidine Dihydrochloride, Chlorhexidine Digluconate, Chlorhexidine Diacetate) are used in the formulation of eye makeup, makeup foundations, mouthwashes, hair dyes and bleaches,and other skin care and hair care products;
  2) Chlorhexidine has been used in medical practice and these ingredients, particularlythe Digluconate salt, have extensive use in dentistry because they inhibit plaque formation;
  3) Chlorhexidine is used as a topical antiseptic skin scrub in hospital and household settings;
  4) For use in animals, it is used as a topical disinfectant of wounds.

 

 

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