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Levamisole hydrochloride, also known as levamisole HCl, is the hydrochloride salt form of levamisole. It is the most commonly used and readily available form of levamisole for medical and veterinary purposes. Here are some important points about levamisole hydrochloride:

Antiparasitic: Levamisole hydrochloride is primarily used as an anthelmintic medication in veterinary medicine to treat worm infections in animals. It is effective against various gastrointestinal and lungworm parasites.

Immunomodulatory Effects: Levamisole hydrochloride has also been found to have immunomodulatory properties in humans. It can stimulate the immune system by enhancing the activity of certain white blood cells, such as T-cells and natural killer cells. Due to these effects, levamisole hydrochloride has been used off-label as an adjuvant therapy for certain conditions, such as certain types of cancer and autoimmune disorders. However, its off-label use for immunomodulation is not widely accepted and is a subject of ongoing research.

Dosage and Administration: Levamisole hydrochloride is available in various formulations, including tablets and oral suspensions, for veterinary use. The dosage and administration instructions will depend on the specific animal species, the type of infection being treated, and the veterinarian's guidance. For human use, levamisole hydrochloride is not FDA-approved and should only be used under the supervision of a healthcare professional.

Side Effects: Common side effects of levamisole hydrochloride in animals may include gastrointestinal disturbances, allergic reactions, and neurotoxic effects. In humans, adverse effects can include nausea, vomiting, abdominal pain, dizziness, headache, skin reactions, and changes in blood cell count. Serious side effects, such as agranulocytosis (severe reduction in white blood cells) or vasculitis (inflammation of blood vessels), have been reported in rare cases.