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Levamisole is a medication that was originally developed as an antiparasitic drug for veterinary use. It belongs to the class of drugs known as anthelmintics, which are used to treat and prevent worm infections. However, it has also been used off-label for various other purposes. Here are some important points about levamisole:

Antiparasitic: Levamisole was initially developed to treat worm infections in animals, particularly in livestock. It works by interfering with the nervous system of the parasites, leading to paralysis and eventual elimination from the body.

Veterinary Use: Levamisole is still used as an anthelmintic in veterinary medicine, primarily for the treatment of gastrointestinal and lungworm infections in animals. It is not recommended for use in humans as an antiparasitic drug.

Immunomodulatory Effects: Levamisole has been found to have immunomodulatory properties, meaning it can affect the immune system. It has been used off-label in humans to boost immune function or as an adjuvant treatment for certain conditions, such as certain types of cancer or autoimmune disorders. However, this usage is controversial and not widely accepted.

Side Effects: When used as an antiparasitic, levamisole can cause side effects such as nausea, vomiting, abdominal pain, diarrhea, dizziness, and headache. Allergic reactions, including rash and itching, have also been reported. Off-label use for immunomodulatory purposes may have additional side effects and risks.

Precautions: Levamisole should be used under the guidance of a healthcare professional. It is important to follow the recommended dosage and duration of treatment. Levamisole is contraindicated in individuals with a known allergy to the drug or those with certain medical conditions, such as severe liver or kidney disease.