CAS No.120511-73-1

Chemical Name:Anastrozole

SynonymsARIMIDEX;ANASTRAZOLE;Anastrozol;MDPT;zd;Anatrozole;Arimidex(Anastrozole);ZD-1033;Anastrol;Astrozole

CBNumber:CB3121715

Molecular Formula:C17H19N5

Molecular Weight:293.37

Melting point 81-82°C

Boiling point 469.7±55.0 °C(Predicted)

Density 1.08±0.1 g/cm3(Predicted)

storage temp. room temp

solubility DMSO: soluble40mg/mL

pka 2.62±0.10(Predicted)

form solid

Uses

Anastrozole has significant effects on breast cancer treatment and, therefore, it is currently used as first-line treatment in estrogen receptor (ER)-positive postmenopausal women, particularly to treat locally advanced or metastatic breast cancer. Furthermore, it is also indicated for early cancer treatment, tumor chemoprevention and postmenopausal women using tamoxifen, especially if the drug is used during a prolonged period of time and has been indicated in the disease’s recurrence, i.e., as another therapeutic endocrine option.