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Ketamine can induce a state of sedation (feeling calm and relaxed), immobility, relief from pain, and amnesia (no memory of events while under the influence of the drug). Ketamine has also been used to facilitate sexual assault.

Ketamine is an approved medical product as an injectable, short-acting anesthetic for use in humans and animals and as esketamine (Spravato®; the active form of the drug) as a nasal spray for treatment resistant depression.

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