Linaclotide

CAS NO.: 851199-59-2

Targets Guanylate Cyclase

Molecular Formula C59H79N15O21S6

Molecular Weight 1526.74

Purity ≥95%

Related CAS 851199-60-5 (acetate salt) 1863191-43-8 (TFA salt)

Appearance White Solid

Synonyms

Constella; Linzess; L-Tyrosine, L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1→6),(2→10),(5→13)-tris(disulfide); L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparagyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonyl-glycyl-L-cysteinyl-L-tyrosine (1->6),(2->10),(5->13)-tris(disulfide); H-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH (Disulfide bridge: Cys1-Cys6, Cys2-Cys10, Cys5-Cys13)

Solubility Soluble in DMSO (Slightly, Heated), Methanol (Slightly, Heated), Water (Slightly, Heated)

Storage Store at -20°C

Linaclotide is a peptide agonist of guanylate cyclase 2C that is undergoing clinical trials for use in treating abdominal pain in patients with irritable bowel syndrome (IBS) accompanied by constipation. The drug also has promising outlooks for the treatment of gastroparesis, ulcerative colitis, chronic intestinal pseudo-obstruction (CIPO), and inertia coli as well.

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Pasireotide

CAS NO.: 396091-73-9

Related CAS

820232-50-6 (diaspartate) 396091-77-3 (L-aspartate)

Synonyms

Pasireotide; SOM230; SOM-203; SOM 203; Signifor

Molecular Formula C58H66N10O9

Molecular Weight 1047.227

Pasireotide is a somatostatin analog with a 40-fold increased affinity to somatostatin receptor 5 compared to other somatostatin analogs.

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CAS: 395723-23-1    MTTA
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CAS: 4551-92-2         2fdck
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CAS: 2732926-24-6  N-Desethyl Isotonitazene

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CAS No.108736-35-2

Chemical Name:Lanreotide

Synonyms

IPSTYL;AUTOGEL;DC-13-116;BIM-23014;LANREOTIDE;bim-23014c;Somatuline;ANGIOPEPTIN;LaroMustine;Lanreotide USP/EP/BP

CBNumber:CB6190280

Molecular Formula:C54H69N11O10S2

Molecular Weight:1096.32

Appearance: White to off-white lyophilized powder

Assay :≥99.00%

Density: 1.4±0.1 g/cm3

Boiling Point: 1508.2℃ at 760mmHg

Flash Point: 865.9℃

Refractive Index: 1.689

Storage Condition: -20℃

Vapor Pressure: 0mmHg at 25℃

Lanreotide (INN) is a medication used in the management of acromegaly and symptoms caused by neuroendocrine tumors, most notably carcinoid syndrome. It is a long-acting analogue of somatostatin, like octreotide. 

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CAS No. 69558-55-0

Chemical Name: Thymopentin

Synonyms

TP-5;RKDVY;Immunox;Timunox;ORF-15244;Thyopentin;THYMOPETIN;THYMOPENTIN;Thymopentine;ThymopentinⅡ

CBNumber: CB7491069

Molecular Formula: C30H49N9O9

Molecular Weight: 679.77

Density 1.44±0.1 g/cm3(Predicted)

storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

solubility DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 10 mg/ml

form Powder

pka 3.07±0.10(Predicted)

color White

Introduction of Thymopentin 69558-55-0:

Pharmacological effects:
Cell immunoregulatory drugs, can induce T cell differentiation and promote the development of T lymphocyte subsets, mature and activation function, and to adjust the proportion of lymphocyte subsets, it close to normal.

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CAS: 14680-51-4     Metonitazene
CAS: 119276-01-6   Protonitazene hydrochloride
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CAS: 2785346-75-8 Etonitazepyne
CAS: 28578-16-7      PMK
CAS: 20320-59-6      BMK
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CAS: 17764-18-0      Eutylone
CAS: 395723-23-1    MTTA
CAS: 4551-92-2         2fdck
5CL-ADBA  ADBB  A-PVP  jwh-018
CAS: 2732926-24-6  N-Desethyl Isotonitazene

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